저널명 : Chemical Society Reviews, 46, 2237-2271 (2017) 
저자 : Min Gao, Fabiao Yu*, Changjun Lv, Jaebum Choo* and Lingxin Chen* 
기타사항 :  

Abstract

Surgical resection of solid tumors is currently the gold standard and preferred therapeutic strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting the rapid growth of tumor cells and these two approaches are often combined to enhance treatment efficacy. However, surgery and chemotherapy inevitably lead to severe side effects and high systemic toxicity, which in turn results in poor prognosis. Precision medicine has promoted the development of treatment modalities that are developed to specifically target and kill tumor cells. Advances in in vivo medical imaging for visualizing tumor lesions can aid diagnosis, facilitate surgical resection, investigate therapeutic efficacy, and improve prognosis. In particular, the modality of fluorescence imaging has high specificity and sensitivity and has been utilized for medical imaging. Therefore, there are great opportunities for chemists and physicians to conceive, synthesize, and exploit new chemical probes that can image tumors and release chemotherapy drugs in vivo. This review focuses on small molecular ligand-targeted fluorescent imaging probes and fluorescent theranostics, including their design strategies and applications in clinical tumor treatment. The progress in chemical probes described here suggests that fluorescence imaging is a vital and rapidly developing field for interventional surgical imaging, as well as tumor diagnosis and therapy.


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List of Articles
제목 저널명 저자 기타사항

2017 Biomedical Applications of SERS Spectroscopy

저널명 In “Frontiers and Advances in Molecular Spectroscopy“, Book Chapter 9 (2017), Elsevier. 

저자 Rui Wang, Hyangah Chon, Sangyeop Lee, Juhui Ko, Joonki Hwang, Namhyun Choi, Ziyi Cheng, Xiaokun Wang and Jaebum Choo* 

기타사항 Book Chapter 

2017 Surfactant-Free Vapor-Phase Synthesis of Single-crystalline Gold Nanoplates fo...

저널명 Chemistry of Materials, in press. 

저자 Y. Yoo, H. Lee, H. Lee, M. Lee, S. Yang, A. Hwang, S. Kim, J. Y. Park, J. Choo, T. Kang* and B Kim* 

기타사항  

2017 An integrated SERS-based microdroplet platform for the automated immunoassay of... file

저널명 Analytical Chemistry, 89, 8413-8420 (2017) 

저자 Namhyun Choi, Jiyoung Lee, Juhui Ko, Jun Ho Jeon, Gi-eun Rhie, Andrew deMello* and Jaebum Choo* 

기타사항  

2018 Nanoscale graphene oxide-induced metallic nanoparticle clustering for SERS-bas... file

저널명 Sensors & Actuators B, 255, 183-192 (2018) 

저자 Ahmed Ali, Eun Young Hwang, Jaebum Choo and Dong Woo Lim* 

기타사항  

2017 Analysis of ribonuclease activity in sub-nanoliter droplets by label-free fluo... file

저널명 Analyst, 142, 2610-2616 (2017) 

저자 Jae-Won Choi, Bala M. K. Vasamsetti, Kyu-Wan Kim, Seung Hwan Seo, Dong-Hun Lee, Soo-Ik Chang, Jaebum Choo* and Hak Yong Kim* 

기타사항  

2017 SERS-based genetic assay for amplification-free detection of prostate cancer ... file

저널명 Sensors & Actuators B, 251, 302-309 (2017) 

저자 Jimin Yu, Jinhyeok Jeon, Namhyun Choi, Jin Oh Lee, Young-Pil Kim and Jaebum Choo* 

기타사항  

2017 Simultaneous detection of dual prostate specific antigens using SERS-based immun... file

저널명 ACS Nano, 11, 4926-4933 (2017) 

저자 Ziyi Cheng, Namhyun Choi, Rui Wang, Sangyeop Lee, Kyung Chul Moon, Soo-Young Yoon, Lingxin Chen* and Jaebum Choo* 

기타사항  

2017 From single-molecule detection to next-generation sequencing: microfluidic dro... file

저널명 Microfluidics and Nanofluidics, 21:58 (2017) 

저자 Yun Ding, Jaebum Choo and Andrew deMello* 

기타사항  

2017 Fluorescent chemical probes for accurate tumor diagnosis and targeting therapy file

저널명 Chemical Society Reviews, 46, 2237-2271 (2017) 

저자 Min Gao, Fabiao Yu*, Changjun Lv, Jaebum Choo* and Lingxin Chen* 

기타사항  

2017 Quantum Dot–based Molecularly Imprinted Polymers on Three-Dimensional Origami ... file

저널명 ACS Sensors, 2, 243-250 (2017) 

저자 Bowei Li, Zhong Zhang, Ji Qi, Na Zhou, Song Qin, Jaebum Choo* and Lingxin Chen* 

기타사항  


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