저널명 : ACS Omega, 3, 10084-10091 (2018) 
저자 : Oliver Dressler, Philip Howes, Jaebum Choo and Andrew deMelllo* 
기타사항 :  

Abstract

Recent years have witnessed an explosion in the application of microfluidic techniques to a wide variety of problems in the chemical and biological sciences. Despite the many considerable advantages that microfluidic systems bring to experimental science, microfluidic platforms often exhibit inconsistent system performance when operated over extended timescales. Such variations in performance are because of a multiplicity of factors, including microchannel fouling, substrate deformation, temperature and pressure fluctuations, and inherent manufacturing irregularities. The introduction and integration of advanced control algorithms in microfluidic platforms can help mitigate such inconsistencies, paving the way for robust and repeatable long-term experiments. Herein, two state-of-the-art reinforcement learning algorithms, based on Deep Q-Networks and model-free episodic controllers, are applied to two experimental “challenges,” involving both continuous-flow and segmented-flow microfluidic systems. The algorithms are able to attain superhuman performance in controlling and processing each experiment, highlighting the utility of novel control algorithms for automated high-throughput microfluidic experimentation.


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List of Articles
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2019 High-throughput Microfluidic Imaging Flow Cytometry file

저널명 Current Opinion in Biotechnology, 55, 36-43 (2019) 

저자 Stavros Stavrakis, Gregor Holzner, Jaebum Choo* and Andrew deMello* 

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2019 Modification of Phage Display Technique for Improved Screening of High-Aff...

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2018 Cut-and-Paste Transferrable Pressure Sensing Cartridge Films file

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저자 H. Hwang, S. E. Choi, S. W. Han, I. You, E. S. Jeong, S. Kim, H. Yang, S. Lee, J. Choo, J. W. Kim* and U. Jeong* 

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저자 H. Yang, Z. Chen, X. Cao, Z. Li, S. Stavrakis, J. Choo, A. J. deMello,* P. D. Howes and N. He* 

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2018 Reinforcement Learning for Dynamic Microfluidic Control file

저널명 ACS Omega, 3, 10084-10091 (2018) 

저자 Oliver Dressler, Philip Howes, Jaebum Choo and Andrew deMelllo* 

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2018 Application of SERS-based Microfluidics for In Vitro Diagnostics

저널명 In “Medical and Biological Applications Using Microfluidic Devices”, Book Chapter 9 (2018) in press, Springer. 

저자 Jinhyeok Jeon, Namhyun Choi, Joung-il Moon, Hao Chen and Jaebum Choo* 

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저자 T. Yang, J. Choo, S. Stavrakis* and A. deMello* 

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