저널명 : Sensors & Actuators B, 270, 72-79 (2018) 
저자 : Rui Wang, Kihyun Kim, Namhyun Choi, Xiaokun Wang, Jiyoung Lee, Jun Ho Jeon, Gi-eun Rhie and Jaebum Choo* 
기타사항 :  

Abstract

Bacterial pathogens such as Yersinia pestis, Francisella tularensis, and Bacillus anthracis are classified intothe highest rank of potential bioterrorism agents. Colorimetric lateral flow assay (LFA) strips are com-mercially available but these conventional strips have drawbacks in terms of low sensitivity and limitof quantitative analysis. Therefore, there is an urgent need for a new sensing platform to detect thesepathogens in the early contamination stage. In this study, a novel surface-enhanced Raman scattering(SERS)-based LFA strip was developed for sensitive detection of bacterial pathogens. Target-specific SERSnanotags (Raman reporter-labeled gold nanoparticles) were used as an alternative to the gold nanopar-ticles in conventional LFA strips. Using these SERS nanotags the presence of bacteria could be identifiedthrough a simple color change in the test line. Additionally, highly sensitive and accurate quantitativeanalysis could be performed by monitoring the characteristic Raman peak intensity of SERS nanotagsthat were captured in the test line. This highly sensitive method required a short assay time (15 min) anda tiny volume of pathogen sample (40 μL). We believe that the proposed SERS-based LFA technique hasgreat potential as a valuable tool in the early detection of specific bacterial pathogens in the field due toits excellent analytical sensitivity.


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List of Articles
제목 저널명 저자 기타사항

2018 Application of SERS-based Microfluidics for In Vitro Diagnostics

저널명 In “Medical and Biological Applications Using Microfluidic Devices”, Book Chapter 9 (2018) in press, Springer. 

저자 Jinhyeok Jeon, Namhyun Choi, Joung-il Moon, Hao Chen and Jaebum Choo* 

기타사항 Book Chapter 

2018 High-throughput Microfluidic Imaging Flow Cytometry

저널명 Current Opinion in Biotechnology, in press. 

저자 Stavros Stavrakis, Gregor Holzner, Jaebum Choo* and Andrew deMello* 

기타사항  

2018 Fluoropolymer Coated PDMS Microfluidic Devices for Application in Organic ...

저널명 Chemistry - A European Journal, in press. 

저자 T. Yang, J. Choo, S. Stavrakis* and A. deMello* 

기타사항  

2018 Sensitive and Reproducible Immunoassay of Multiple Mycotoxins Using Surface-En...

저널명 Small, in press. 

저자 Xiaokun Wang, Sung-Gyu Park, Juhui Ko, Xiaofei Xiao, Vincenzo Giannini, Stefan A. Maier, Dong-Ho Kim,* Jaebum Choo* 

기타사항  

2018 Plasmonic Colorimetric Sensors Based on Etching and Growth of Noble Metal ... file

저널명 Biosensors & Bioelectronics, 114, 52-65 (2018) 

저자 Z. Zhang, H. Wang, Z. Chen, X. Wang, J. Choo* and L. Chen* 

기타사항  

2018 Highly Sensitive Detection of High-risk Bacterial Pathogens Using SERS-based ... file

저널명 Sensors & Actuators B, 270, 72-79 (2018) 

저자 Rui Wang, Kihyun Kim, Namhyun Choi, Xiaokun Wang, Jiyoung Lee, Jun Ho Jeon, Gi-eun Rhie and Jaebum Choo* 

기타사항  

2018 PEGylated Nanographene–mediated Metallic Nanoparticle Clusters for Surface En... file

저널명 Analyst, 143, 2604-2615 (2018) 

저자 Ahmed Ali , Eun Young Hwang , Jaebum Choo and Dong Woo Lim* 

기타사항  

2018 M13 Bacteriophage/Silver Nanowire Surface-Enhanced Raman Scattering Sensor fo... file

저널명 ACS Applied Materials & Interfaces, 10, 10388-10397 (2018) 

저자 Eun Hye Koh, ChaeWon Mun, Chun Tae Kim, Sung-Gyu Park, Eun Jung Choi, Sun Ho Kim, Jaejeung Dang, Jaebum Choo, Jin-Woo Oh, Dong-Ho Kim* and Ho Sang Jung* 

기타사항  

2018 Culture-free Detection of Bacterial Pathogens on Plasmonic Nanopillar Arrays... file

저널명 ACS Applied Materials & Interfaces, 10, 6831-6840 (2018) 

저자 Juhui Ko, Sung-Gyu Park, Sangyeop Lee, Xiaokun Wang, Chaewon Mun, Sunho Kim, Dong-Ho Kim* and Jaebum Choo* 

기타사항  

2018 Nanoscale graphene oxide-induced metallic nanoparticle clustering for surface-e... file

저널명 Sensors & Actuators B, 255, 183-192 (2018) 

저자 Ahmed Ali, Eun Young Hwang, Jaebum Choo and Dong Woo Lim* 

기타사항  


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