저널명 : Chemical Society Reviews, 46, 2237-2271 (2017) 
저자 : Min Gao, Fabiao Yu*, Changjun Lv, Jaebum Choo* and Lingxin Chen* 
기타사항 :  

Abstract

Surgical resection of solid tumors is currently the gold standard and preferred therapeutic strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting the rapid growth of tumor cells and these two approaches are often combined to enhance treatment efficacy. However, surgery and chemotherapy inevitably lead to severe side effects and high systemic toxicity, which in turn results in poor prognosis. Precision medicine has promoted the development of treatment modalities that are developed to specifically target and kill tumor cells. Advances in in vivo medical imaging for visualizing tumor lesions can aid diagnosis, facilitate surgical resection, investigate therapeutic efficacy, and improve prognosis. In particular, the modality of fluorescence imaging has high specificity and sensitivity and has been utilized for medical imaging. Therefore, there are great opportunities for chemists and physicians to conceive, synthesize, and exploit new chemical probes that can image tumors and release chemotherapy drugs in vivo. This review focuses on small molecular ligand-targeted fluorescent imaging probes and fluorescent theranostics, including their design strategies and applications in clinical tumor treatment. The progress in chemical probes described here suggests that fluorescence imaging is a vital and rapidly developing field for interventional surgical imaging, as well as tumor diagnosis and therapy.


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List of Articles
제목 저널명 저자 기타사항

2017 Fluorescent chemical probes for accurate tumor diagnosis and targeting therapy file

저널명 Chemical Society Reviews, 46, 2237-2271 (2017) 

저자 Min Gao, Fabiao Yu*, Changjun Lv, Jaebum Choo* and Lingxin Chen* 

기타사항  

2017 Quantum Dot–based Molecularly Imprinted Polymers on Three-Dimensional Origami ... file

저널명 ACS Sensors, 2, 243-250 (2017) 

저자 Bowei Li, Zhong Zhang, Ji Qi, Na Zhou, Song Qin, Jaebum Choo* and Lingxin Chen* 

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2017 Spectroscopic measurements of interactions between hydrophobic 1-pyrenebutyric... file

저널명 Colloids and Surfaces A, 518, 295-303 (2017) 

저자 Nguyen Hoang Ly, Thanh Danh Nguyen, Thanh Lam Bui, Sangyeop Lee, Jaebum Choo, Sang-Woo Joo* 

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2017 Raman spectrum identification based on the correlation score using weighted ... file

저널명 Analyst, 142, 380-388 (2017) 

저자 Jun-Kyu Park, Aaron Park, Si Kyung Yang, Sung-June Baek*, Joonki Hwang and Jaebum Choo* 

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2017 Simultaneous Detection of Dual Nucleic Acids Using a SERS-based Lateral Flow... file

저널명 Analytical Chemistry, 89, 1163-1169 (2017) 

저자 Xiaokun Wang, Namhyun Choi, Ziyi Cheng, Juhui Ko, Lingxin Chen*, and Jaebum Choo* 

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2017 Optical nanoprobes for ultrasensitive immunoassay file

저널명 Analytical Chemistry, 89, 124-137 (2017) 

저자 Xiuli Fu, Lingxin Chen* and Jaebum Choo* 

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2017 Interfacial structures of 1-methyladenine, 3-methyladenine, 7-methyladenine, and... file

저널명 Journal of Molecular Structure, 1128, 215-220 (2017) 

저자 Dinh Bao Nguyen, Sang-Woo Joo* and Jaebum Choo* 

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2017 Quantitative analysis of thyroid-stimulating hormone (TSH) using SERS-based later... file

저널명 Sensor and Actuators B, 240, 358-364 (2017) 

저자 Suji Choi, Joonki Hwang, Sangyeop Lee, Dong Woo Lim, Hoodon Joo, and Jaebum Choo* 

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2016 Streptavidin-triggered signal amplified fluorescence polarization for analysis o... file

저널명 Analyst, 141, 6499-6502 (2016) 

저자 Jae-Won Choi, Byung-Gwan Jo, Andrew deMello*, Jaebum Choo* and Hak Yong Kim* 

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2016 Early Diagnosis of Influenza Virus A Using SERS-based Lateral Flow Assay file

저널명 Bulletin of the Korean Chemical Society, 37, 2019-2024 (2016) 

저자 Hyun Ji Park, Sung Chul Yang and Jaebum Choo* 

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